一些研究表明褪黑激素对人体月经周期有作用。对人类黄体孕酮分泌的研究显示出药理剂量的褪黑激素对卵巢有直接作用。当前研究的目标是确定生理浓度的褪黑激素是否能直接作用于卵巢。对健康妇女24小时外周血标本的研究证实褪黑激素的浓度波动范围白天从测不出到50pgml~(-1)之间,夜间上升至50—200pgml~(-1)。 Some studies suggest that melatonin has a role in the body’s menstrual cycle. Studies on the secretion of progesterone in human lutein have shown that pharmacological doses of melatonin have a direct effect on the ovary. The goal of the current study is to determine whether physiological concentrations of melatonin act directly on the ovary. A 24-hour study of peripheral blood samples from healthy women confirmed that the concentration range of melatonin fluctuated from no detectable to 50 pgml-1 during the day and increased to 50-200 pgml-1 during the night.