血栓性血小板减少性紫癜(TTP),系Moschco-witz于1925年首先描述,故也称为Moschcowitz综合征。迄止1981年,国外文献报道546例,国内至今公开报道的约10例。本病可见于任何年龄,但大多数在10～40岁之间,女与男之比为3:2。一、致病因素及发病机理 (一)致病因素,本病的病因迄今未明,可能与下列因素有关:(1)药物:应用青霉素、四环素、磺 Thrombotic thrombocytopenic purpura (TTP), Department of Moschco-witz first described in 1925, it is also known as Moschcowitz syndrome. Up to 1981, 546 cases were reported in foreign literature and about 10 cases were reported publicly in China so far. The disease can be seen at any age, but most of the 10 to 40 years old, the ratio of women to men is 3: 2. First, the risk factors and pathogenesis (A) pathogenic factors, the etiology of the disease so far unknown, may be related to the following factors: (1) drugs: the application of penicillin, tetracycline, sulfonamide