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新近研究显示,使用单剂伊维菌素(150—200mg/kg)治疗粪类圆线虫感染,效果显著。然而,由于患者粪便中粪类圆线虫幼虫数量极少,难以用常规粪检法检获,对药效评估带来困难。本文作者首次对服药后的患者各类血清抗体进行长期动态观察,试图测定何型抗体更适于做为粪类圆线虫感染的免疫流行病学研究指标。
Recent studies have shown that the use of a single dose of ivermectin (150-200mg / kg) treatment of stool nematode infection, the effect is significant. However, due to the very small number of stool nematode larvae found in the stools of patients, it is difficult to be seized by conventional stool tests, which makes it difficult to assess efficacy. For the first time, the authors make long-term dynamic observation of various serum antibodies in patients after taking the medicine and try to determine which antibody is more suitable as an immune epidemiological study index for infection of stool worms.