论文部分内容阅读
传染性单核细胞增多症(简称IM)目前已用免疫萤光素方法来测定本病E-B病毒(简称EBV)抗体的存在,以助诊断。本文对疑有IM的22例儿童进行了研究。所有病例均作了以下检查:①全血细胞计数;②嗜异凝集试验;③单核细胞增多试验;以及④EBV抗体测定。这些病例仅在血片中出现10％或更多的不典型单核细胞,而嗜异凝集试验和单核细胞增多试验均属阴性,但在21例证明有EBV抗体存在。另外对照组27例(其他疾病),血片中未发现异常单核细胞,仅有5例患儿有EBV抗体。本组22例中,有15例患儿最初的EBV抗体滴度<1∶10,但在1月或更长的时间,其滴度即升高到1∶10～1∶100。4例患儿在病初的EBV抗体滴度为1∶10,至1～2月后明显升达1∶50～1∶100。2例患儿在随查中,抗体滴度有所下降。仅有1例一直为阴性结果。因此,凡有EBV抗体滴度升高,即可支持IM的诊断。近年来,已确认IM和类疱疹病毒之间有密切关系,称为E-B病毒。该病毒首先被电子显微镜所检
Infectious mononucleosis (IM) has been used immunofluorescein method to determine the presence of the disease E-B virus (referred to as EBV) antibodies to help diagnose. In this paper, 22 cases of suspected IM patients were studied. All cases were made the following checks: ① complete blood count; ② heterophile aggregation test; ③ mononucleosis test; and ④ EBV antibody. In these cases, only 10% or more of atypical monocytes appeared in the blood films, whereas both the heterophilic agglutination test and the mononucleosis test were negative, but EBV antibodies were found in 21 cases. In addition, 27 cases (other diseases) in the control group showed no abnormal monocytes in the blood film, and only 5 children had EBV antibody. The group of 22 cases, 15 cases of children with initial EBV antibody titer <1:10, but in January or longer, the titer that rose to 1:10 ~ 1: 100.4 patients At the beginning of the illness, the antibody titer of EBV antibody was 1:10, and the titer reached 1:50 ~ 1: 100 after 1 ~ 2 months. Only one patient has been negative. Therefore, any increase in EBV antibody titer can support the diagnosis of IM. In recent years, it has been confirmed that there is a close relationship between IM and herpes simplex virus, called E-B virus. The virus was first examined by the electron microscope