目的　观察大深度快速上浮脱险对潜艇艇员生命指征的影响。方法　分别进行了 3,10 ,6 0 ,80 ,10 0 ,12 0和 15 3m 4 0人次的快速上浮脱险实验 ,于脱险前和脱险后观察艇员血压、脉率及呼吸频率的改变。结果　脱险后 ,艇员收缩压、舒张压、脉率和呼吸频率均有所增加 ,在出舱后即刻为甚 ,大部分指标在出舱后即刻与进舱前相比较 ,差异有显著性 (P<0 .0 5 )或有非常显著性 (P<0 .0 1)。在出舱后 10min各指标基本恢复正常。在 10 0 ,12 0和 15 3m快速上浮脱险时第 1名艇员脉率改变持续较久 ,但最终也恢复正常。结论　快速上浮脱险可增加艇员血压、脉率和呼吸频率 ,但均为一过性。本次实验脱险方案是安全可靠的 Objective To observe the effect of rapid expedition on the vital signs of submarine crew. Methods Rapid escaping experiments of 3, 10, 60, 80, 100, 120 and 153m 4 were carried out respectively. Changes of blood pressure, pulse rate and respiration rate were observed before and after escapement. As a result, the contractile pressure, diastolic blood pressure, pulse rate and respiratory rate of the crew increased after the accidental escape, immediately after the exit, most of the indicators were significantly different from those before entering the cabin P <0.05) or very significant (P <0.01). 10min after the exit of the index returned to normal. At 10 0, 12 0 and 15 3m rapid take-off, the first crew member changed its pulse rate to last longer, but eventually returned to normal. Conclusions The rapid ascension can increase the blood pressure, pulse rate and respiratory rate of sailors, but they are transient. The experimental escapement program is safe and reliable