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目的:探讨大容量全肺灌洗术对早期尘肺的方法、临床疗效及应用价值。方法:将122例早期尘肺受试患者按接诊时间分为单肺组62例,双肺组60例,双肺组患者采用双肺同期大容量全肺灌洗术,单肺组患者采用单肺分期大容量全肺灌洗术,对其资料进行回顾性分析。结果:双肺组患者FVC、VC、FEV1、MVV以及25%、50%、75%FVC时患者用力呼流量(FEF75、FEF50、FEF25)均明显高于单肺组,比较具有显著差异(P<0.05);双肺组患者并发症发生率明显高于单肺组,具有极显著差异(P<0.01)。结论:双肺同期灌洗术对患者肺功能的改善效果更佳,但应注意对患者机体耐受性的评估,避免灌洗时间过长,以减少并发症的发生。
Objective: To explore the method, clinical curative effect and application value of high-capacity whole lung lavage for early pneumoconiosis. Methods: One hundred and twenty-two patients with early pneumoconiosis were divided into single lung group (62 cases), double lung group (60 cases), double lung group with large-capacity whole lung lavage at the same period, single lung group Pulmonary high-volume pulmonary lavage staging, its data were retrospectively analyzed. Results: The forced expiratory flow (FEF75, FEF50, FEF25) of patients with dual lung group were significantly higher than that of single lung group (FVC, VC, FEV1, MVV and 25%, 50%, 75% 0.05). The incidence of complications in patients with lung group was significantly higher than that in patients with single lung group (P <0.01). Conclusions: Lungs simultaneous lavage of double lungs have a better effect on improving lung function. However, we should pay attention to the assessment of patient tolerance and avoid prolonged lavage to reduce the incidence of complications.