论文部分内容阅读
建立复方甲硝唑注射液中氯霉素和甲硝唑的系数倍率测定法。用BASIC语言编制程序选择最佳测定波长对,以消除二组分的相互干扰,不经提取分离同时测定复方甲硝唑注射液中氯霉素和甲硝唑的含量。氯霉素的比尔线性范围为9.890～32.13μg/ml,r=0.9995;甲硝唑的比尔线性范围为10.09～30.28μg/ml,r=0.9992。复方甲硝唑注射液中氯霉素和甲硝唑的平均回收率和相对标准偏差分别为100.2%,1.1%和100.8%,1.3%。该方法简便、快速、重现性好、准确度高,可用于复方甲硝唑注射液的质量控制。
To establish a method for determining the ratio of chloramphenicol and metronidazole in compound metronidazole injection. Using BASIC language program to select the best determination of wavelength pairs, in order to eliminate the interference of the two components, without the simultaneous determination of compound metronidazole metronidazole injection metronidazole injection content. The linear range of chloramphenicol was 9.890 ~ 32.13μg / ml, r = 0.9995. The linear range of metronidazole was 10.09 ~ 30.28μg / ml, r = 0.9992. The average recoveries and relative standard deviations of chloramphenicol and metronidazole in compound metronidazole injection were 100.2%, 1.1% and 100.8%, 1.3%, respectively. The method is simple, rapid, reproducible and accurate, and can be used for the quality control of compound metronidazole injection.