Leyll 氏按不同原因将中毒性表皮坏死松解症(TEN)分为①药物型、②葡萄菌型、③混合型和④特发型等四型。其中药物型即杨氏命名为“大疱性表皮松解萎缩型药物性皮炎(BEATDM)”,系一种严重药疹。临床表现以起病急剧,病情危重,特有的广泛性烫伤样损害,多伴高烧,内脏损害和死亡率高为特征。鉴于近十余年本病发病率日趋增多,为引起重视,现将住院41例患者,结合文献作一 Leyll’s different causes of toxic epidermal necrolysis (TEN) is divided into ① drug type, ② grape bacteria, ③ mixed type and ④ idiopathic type four. Among them, the drug named Yang is named as “bullous epidermolytic atrophic drug dermatitis (BEATDM)” and is a serious drug eruption. Clinical manifestations with rapid onset, critical condition, unique extensive scalded lesions, with many high fever, visceral damage and high mortality is characterized. In view of the past ten years the incidence of this disease is increasing, to attract attention, now in hospital 41 patients, combined with the literature for a