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目的:研究探讨消化性溃疡出血应用兰索拉唑联合云南白药治疗的效果,丰富临床治疗经验。方法:选取2011年4月-2014年4月在我院收治并确诊的消化性溃疡出血患者82例,将患者随机分成对照组与观察组各41例。对照组采用兰索拉唑30mg,1次·d-1,晨服;观察组患者在对照组的基础上添加云南白药0.5mg,3次·d-1,餐前1h服用。经10d治疗后统计两组患者的治疗总有效率,并进行比较。结果:经治疗后患者的临床症状均明显改善缓解,观察组治疗的总有效率为95.10%,明显优于对照组的75.60%,比较差异显著(P<0.05),具有统计学意义;观察组患者不良反应发生率为0.00%,与对照组2.40%的不良反应发生率相比,差异不显著(P>0.05),无统计学意义。结论:在治疗消化性溃疡出血方面,兰索拉唑联合云南白药治疗可取得较满意的临床疗效,且治疗期间并未出现不良反应,值得在临床治疗中大力推广应用。
Objective: To study the application of lansoprazole and Yunnanbaiyao in the treatment of peptic ulcer bleeding, and to enrich clinical experience. Methods: 82 patients with peptic ulcer hemorrhage admitted to our hospital from April 2011 to April 2014 were selected and randomly divided into control group and observation group (n = 41). The control group received lansoprazole 30mg, 1 time · d-1, morning suits; observation group patients in the control group based on the Yunnanbaiyao 0.5mg, 3 times · d-1, 1h before meals. After 10d treatment, the total effective rate of two groups of patients was counted and compared. Results: After treatment, the clinical symptoms of patients were significantly improved. The total effective rate of the observation group was 95.10%, which was significantly better than that of the control group (75.60%) (P <0.05), and the observation group The incidence of adverse reactions in patients was 0.00%, which was not significantly different from the incidence of adverse reactions in control group (2.40%) (P> 0.05). There was no statistical significance. Conclusion: The treatment of peptic ulcer, lansoprazole combined Yunnanbaiyao treatment can be more satisfied with the clinical efficacy, and no adverse reactions during treatment, it is worth to promote the clinical application.