目的提高对肾病综合征（ＮＳ）合并肺动脉血栓栓塞（ＰＴＥ）的认识。方法对３例ＮＳ合并ＰＴＥ患者进行回顾性分析。结果ＮＳ合并ＰＴＥ时，血纤维蛋白原、α２球蛋白、血脂均增高。肾脏病理检查１例患者为膜性肾病。肺灌注通气显像及尸检显示：双肺多发栓塞１例。应用肝素钠和（或）尿激酶治疗有效。结论ＮＳ时存在血液高凝状态，易并发ＰＴＥ。故对ＮＳ高度怀疑ＰＴＥ时，应做肺动脉造影检查。在应用糖皮质激素的基础上抗凝溶栓联合治疗效果最佳。 Objective To improve the understanding of nephrotic syndrome (NS) combined with pulmonary thromboembolism (PTE). Methods Three patients with NS complicated with PTE were retrospectively analyzed. Results When NS combined with PTE, fibrinogen, α2 globulin, and lipids increased. One case of renal pathology was membranous nephropathy. Lung perfusion ventilation imaging and autopsy showed: multiple pulmonary embolism in 1 case. Application of heparin and (or) urokinase treatment is effective. Conclusion The hypercoagulable state of blood exists in the NS and is easily complicated by PTE. Therefore, NS highly suspected PTE, pulmonary arteriography should be done. In the application of glucocorticoid based on anticoagulant thrombolytic combination therapy best.