论文部分内容阅读
The present study deals primarily with the antagonistic effect of Naloxone(NX) against mutual potentiation of morphine (Mor), mek-enkephalin (MEK)and dyno phin (Dyn) in their analgesic effects. (1) The rats were divided into 4 groups, ie. NS, NX 0. 02, 0. 1 and 0. 5mg/kggroups. A mixture of Dyn 2. 5noml and Mot 7. 5noml was injected in thebeginning via intrathecal cannulae into each rat. Percentage incrcase in TFLin all 4 groups was between 94±19% and 109±20% 10rain later. After thateach grcup was injected subcutaneously NS, NX 0.02, 0.1 and 0.5mg/kg respe-ctively and was observed continuously for 50min. The results suggest that the
The present study was originally conducted with the antagonistic effect of Naloxone (NX) against mutual potentiation of morphine (Mor), mek-enkephalin (MEK) and dyno phin (Dyn) in their analgesic effects. , ie NS, NX0.02, 0.1 and 0.5 mg / kg groups. A mixture of Dyn 2. 5noml and Mot 7. 5noml was injected in the beginning via intrathecal cannulae into each rat. Percentage incrcase in TFLin all 4 groups was between 94 ± 19% and 109 ± 20% 10rain later. After thateach grcup was injected subcutaneously NS, NX 0.02, 0.1 and 0.5 mg / kg respe-ctively and was observed continuously for 50 min. The results suggest that the