为探讨运动对骨质疏松症的防治机理 ,对 2 6名绝经后女性健骨运动前后骨代谢调节激素和细胞调节因子的变化进行了比较。结果显示 :科学的健骨运动后锻炼者的血清雌二醇 (E2 )浓度有所增高 ,甲状旁腺激素 (PTH)水平有所下降 ,IL - 6浓度显著下降(P <0 0 1 ) ;组间比较 ,实验前运动组所有指标与对照组相比均无显著性差异 (P >0 0 5) ,实验后运动组IL - 6含量下降 ,与对照组比较P <0 0 1 ,提示健骨运动对绝经后女性的雌激素水平降低有阻遏作用 ,同时对绝经后高转换型骨吸收过程产生抑制效应 ,使其骨代谢的负平衡状况得以改善 To explore the mechanism of exercise prevention and treatment of osteoporosis, the changes of bone metabolism regulatory hormones and cytokines in 26 postmenopausal women during and after bone-setting exercise were compared. The results showed that the level of serum estradiol (E2) increased, the level of parathyroid hormone (PTH) decreased and the concentration of IL - 6 decreased significantly (P <0.01). Compared with the control group, all the indexes in the exercise group before the experiment had no significant difference (P> 0.05), and the IL - 6 level in the exercise group decreased after the experiment, P <0.01 compared with the control group Bone movement suppresses the decrease of estrogen level in postmenopausal women, and at the same time, it has an inhibitory effect on the bone resorption process after high menopause and the negative balance of bone metabolism can be improved