急性冠状动脉综合征(acute coronary syndrome,ACS)是指冠状动脉内不稳定的动脉粥样斑块破裂或糜烂引起血栓形成所导致的心脏急性缺血综合征。临床治疗中,经皮冠脉介入治疗(percutaneous coronary intervention,PCI)占有重要的地位,但PCI时球囊扩张对血管壁产生的压力会引起粥样硬化斑块破裂及内膜、中膜损伤(置入支架更加重血管内皮损伤),引起强烈的血小板活化,促进血小板黏附、聚集和 Acute coronary syndrome (ACS) refers to acute ischemic syndrome caused by thrombosis caused by unstable atherosclerotic plaque rupture or erosion in the coronary artery. In clinical treatment, percutaneous coronary intervention (PCI) occupies an important position. However, the pressure exerted by balloon dilatation on the vascular wall during PCI may cause the rupture of atherosclerotic plaque and the injury of the intima and media ( Into the stent more serious vascular endothelial damage), causing strong platelet activation, promote platelet adhesion, aggregation and