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沙苑子为传统中药之一。对于本药的药理、化学,临床应用报道甚少。本文采用饲喂高脂饲料造成实验性高脂血症,观察血脂的变化。 Ⅰ 药物:沙苑子系豆科植物扁茎黄芪Astragalus Complanatus R.Br.成熟的种子。由本院植化组提取。 Ⅱ 血脂测定:血清总胆固醇含量测定;邻苯二甲醛法。红细胞胆固醇含量测定:醋酸乙酯,无水乙醇抽提,邻苯二甲醛法,血清甘油酯含量测定:正庚烷——异丙醇——乙酰丙酮显色法。高密度脂蛋白——胆固醇含量测定:磷钨酸钠——氯化镁沉淀
Sha Yuanzi is one of the traditional Chinese medicines. For the pharmacology and chemistry of this drug, very few clinical applications have been reported. This article used high fat diets to cause experimental hyperlipidemia and observe changes in blood lipids. I Drugs: Astragalus Complanatus R. Br. mature seeds of Astragalus sp. Extracted by our hospital’s Phytochemical Group. II Determination of blood lipids: determination of serum total cholesterol; o-phthalaldehyde method. Erythrocyte cholesterol content determination: ethyl acetate, ethanol extraction, o-phthalaldehyde, serum glycerol content determination: n-heptane - isopropanol - acetyl acetone color method. High Density Lipoprotein Determination of Cholesterol: Sodium Phosphotungstate - Magnesium Chloride Precipitate