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由于急性胰腺炎早期轻重程度难以判断,因此影响了对此病的恰当处治。现已建立了一些确定此病严重性的前瞻性记分系统(如Ran-son记分系统、Imrie/Glasgow记分系统和A-PACHE记分系统),但这些记分系统过于繁琐,需测定多种项目。此前也有一些单项实验室检查用于评估急性胰腺炎严重性,但这些指标有的不易测定,有的则需症状出现48h后才具有准确性。新近有研究显示尿胰蛋白酶原活化肽(TAP)和血细胞比容(Hct)可作为急性胰腺炎早期严重性标志,为确定两者的准确性,作者进行了前瞻性研究。 方法 研究对象为因腹痛入院且符合急性胰腺炎诊断的连续患者,其血清淀粉酶水平均
As early severity of acute pancreatitis is difficult to determine the severity, thus affecting the proper treatment of the disease. A number of prospective scoring systems (such as the Ran-son scoring system, the Imrie / Glasgow scoring system and the A-PACHE scoring system) have been established to determine the severity of the disease but these scoring systems are too cumbersome and require multiple items to be tested. Previously, there were some single laboratory tests for assessing the severity of acute pancreatitis, but some of these indicators are not easy to measure, while others are required to be accurate 48h after the symptoms appear. Recent studies have shown that urinary trypsinogen (TAP) and hematocrit (Hct) can be used as a marker of early severity of acute pancreatitis. To determine the accuracy of the two, we conducted a prospective study. Methods The subjects were consecutive patients admitted to hospital due to abdominal pain and in line with the diagnosis of acute pancreatitis. The serum amylase levels