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SLE是一种具有多系统损害的自身免疫性疾病。在SLE的内脏损害中,以肾脏损害最为常见,因为后者的主要病理改变和临床表现与许多原发性肾小球肾炎相似,故SLE的肾脏损害又称为LN,有肾病综合征表现者有时也称为狼疮肾病。肾小管一间质损害在SLE也很常见,也有报道引起急性肾功能衰竭。SLE病人临床上30～90％有肾脏受累,平均约2/3;而组织学上(光镜、免疫荧光或电镜检查异常)有肾脏受累者达90～100％;50％以上SLE病人的死因是肾功能衰竭。由此可见肾脏病变的严重性对SLE的预后有直接影响。如能
SLE is an autoimmune disease that has multiple systemic impairments. Among the visceral lesions of SLE, kidney damage is the most common, because the latter’s main pathological changes and clinical manifestations are similar to those of many primary glomerulonephritis, so the renal damage of SLE is also called LN, with manifestations of nephrotic syndrome Sometimes called lupus nephropathy. Tubulointerstitial damage is also common in SLE and has also been reported to cause acute renal failure. SLE patients clinically 30 to 90% have kidney involvement, an average of about 2/3; and histological (light microscopy, immunofluorescence or electron microscopy abnormalities) have kidney involvement of 90 to 100%; 50% of the SLE patients the cause of death It is kidney failure. This shows that the severity of renal disease has a direct impact on the prognosis of SLE. If you can