论文部分内容阅读
目的观察术前骶管注射曲马朵与地塞米松用于小儿术后镇痛的时效及不良反应。方法择期手术患儿56例,随机均分为两组:Ⅰ组骶管注入曲马朵2mg·kg~(-1)和地塞米松1～2 mg·kg~(-1),Ⅱ组注入曲马朵2 mg·kg~(-1),术中氯胺酮维持麻醉。监测呼吸循环有关参数,记录氯胺酮总用量、手术时间。自术毕开始记录镇痛时间,患儿首次自动睁眼时间,并开始疼痛评分。结果两组患儿术前一般情况、术中情况及术后恢复情况无统计学差异(P>0.05),术后镇痛有效率:Ⅰ组24h时点为92.8%(26/28例)、48 h时点为82.1%(23/28例),高于Ⅱ组24 h71.4%(20/28例)、48 h 57.1% (16/28例)(P<0.05);镇痛时间Ⅰ组(41±18)h较Ⅱ组(29±20)h长(P<0.05);术后恶心、呕吐发生率Ⅱ组较Ⅰ组发生率高(P<0.05)。结论骶管注射曲马朵加地塞米松用于小儿术后镇痛效果良好,维持时间较长。
Objective To observe the preoperative caudal caudal injection of tramadol and dexamethasone for postoperative analgesia in children aging and adverse reactions. Methods Fifty-six children undergoing elective surgery were randomly divided into two groups: group Ⅰ was given tramadol 2mg · kg -1 and dexamethasone 1 ~ 2 mg · kg -1, group Ⅱ was injected Tramadol 2 mg · kg ~ (-1), intraoperative ketamine to maintain anesthesia. Monitoring respiratory cycle parameters, record the total amount of ketamine, operation time. Since the onset of pain recorded at the beginning of time, the first time in children with automatic eye open, and the pain score. Results There was no significant difference in preoperative general condition, intraoperative status and postoperative recovery between the two groups (P> 0.05). The effective rate of postoperative analgesia was 92.8% (26/28 cases) in group Ⅰ at 24 hours, 48 h, 82.1% (23/28), higher than that in group Ⅱ, 24 h, 71.4% (20/28), 48 h, 57.1% (16/28) The incidence of nausea and vomiting in group Ⅱ (41 ± 18) h was longer than that in group Ⅱ (29 ± 20) h (P <0.05). Conclusion caudal injection of tramadol plus dexamethasone for postoperative analgesia in children with good effect, maintaining a longer time.