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目的总结无功能性胰岛细胞瘤的诊治经验。方法应用中国医学科学院医学信息研究所“中国生物学医学文献数据库”光盘,检索无功能性胰岛细胞瘤1999年11月至2007年12月的文献报道。结果获得有效文献29篇,共报道无功能性胰岛细胞瘤489例。结合中国医科大学附属第一医院普通外科2002-2007年间手术治疗的无功能胰岛细胞瘤15例,总结其临床表现、诊断、治疗方法及结果。结论无功能胰岛细胞瘤症状缺乏特异性,超声和CT可作为首选的检查方法。外科手术是治疗该病、延长病人生存时间的有效手段。
Objective To summarize the diagnosis and treatment of non-functional islet cell tumor. Methods The report of non-functional islet cell tumor from November 1999 to December 2007 was retrieved from the Institute of Medical Information of Chinese Academy of Medical Sciences and the China Biomedical Medical Literature Database. Results There were 29 valid literatures, 489 cases of non-functional islet cell tumor were reported. Combined with 15 cases of nonfunctioning islet cell tumor treated by surgery in the First Affiliated Hospital of China Medical University from 2002 to 2007, the clinical manifestations, diagnosis, treatment and results were summarized. Conclusion The symptoms of non-functioning islet cell tumor are lack of specificity. Ultrasonography and CT can be the first choice of examination. Surgery is the treatment of the disease, to extend the survival of patients with an effective means.