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目的比较常规体外受精(IVF)和卵胞浆内单精子注射(ICSI)对胚胎冻融结局的影响。方法选取2008年1月至2008年12月在我中心进行胚胎冻融移植的142周期(IVF104周期,ICSI38周期),比较两组患者的临床结局。结果142周期共复苏胚胎375枚,IVF组275枚,ICSI组100枚,两组的复苏胚胎存活率相比无差异(89.09%和87.00%);IVF组妊娠率、种植率分别为38.46%、21.22%,ICSI组分别为34.21%、24.14%,两组相比也无统计学差异(P>0.05)。结论本研究结果提示ICSI对冻融胚胎的存活率和发育潜能没有显著影响。
Objective To compare the effects of routine in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) on embryo freeze-thaw outcomes. Methods 142 cycles (IVF104 cycles, ICSI38 cycles) of frozen-thawed embryo transfer from January 2008 to December 2008 in our center were selected. The clinical outcomes of the two groups were compared. Results There were 375 embryos recovered in the 142 cycles, 275 in the IVF group and 100 in the ICSI group. There was no difference between the two groups (89.09% and 87.00%) in the survival rate of embryos resuscitated. The pregnancy rate and implantation rate in the IVF group were 38.46% 21.22% in the ICSI group, 34.21% in the ICSI group and 24.14% in the ICSI group respectively. There was no significant difference between the two groups (P> 0.05). Conclusions The results of this study suggest that ICSI has no significant effect on the survival and developmental potential of frozen-thawed embryos.