论文部分内容阅读
目的探讨重型肝炎内毒素水平与病情及预后的关系。方法将100例重型肝炎患者分三期,按预后分康复组与死亡组,另将26例健康志愿者作为对照组。采用鲎试剂改良基质显色法定量测定空腹静脉血中内毒素含量。结果肝衰竭三期组明显高于对照组(P<0.01);肝功能衰竭后期组明显高于前期组(P<0.01);死亡组明显高于康复组(P<0.01)。结论重型肝炎内毒素水平与病情、预后呈密切相关性。
Objective To investigate the relationship between the severity of hepatitis and the prognosis of severe hepatitis. Methods 100 cases of severe hepatitis patients were divided into three phases, according to the prognosis of the rehabilitation group and the death group, another 26 healthy volunteers as the control group. Quantitative determination of endotoxin in fasting venous blood by limulus reagent modified matrix colorimetry. Results The levels of liver failure in the third phase group were significantly higher than those in the control group (P <0.01); those in the late liver failure group were significantly higher than those in the pre-treatment group (P <0.01); those in the death group were significantly higher than those in the rehabilitation group (P <0.01). Conclusion The level of endotoxin in severe hepatitis is closely related to the disease and prognosis.