乳房癌转移至皮肤所引起的临床症状可与许多炎症性皮肤病相类似,报告1例曾被误诊为冻疮。 患者女,45岁。因右拇趾疼痛性病变6周于当年12月底就诊。末梢轻度发绀,触之皮温较低,局部有2处具触痛的紫色斑块。病史回顾18个月前因乳房癌作过乳房切除术,当时无淋巴结转移。根据病史、临床表现、发病季节和末梢低温等诊断为冻疮。随后肿胀和疼痛加重,1个月后在先前右拇趾冻疮部和右足出现了几个有触痛的、半透明状出血性结节,皮肤活检为与原发的乳房癌相一致的转移腺癌,对上述病变进行局部放疗。 The clinical symptoms caused by the metastasis of breast cancer to the skin can be similar to many inflammatory skin diseases, and 1 case was reported as having been mistaken for frostbite. Patient female, 45 years old. Painful lesions of the right hallux were presented at the end of December of the 6th week. The tip of the hair was slightly numb and the skin temperature was low. There were two patches of purple with tenderness. A history review of breast cancer was performed 18 months ago. There was no lymph node metastasis. Chilblains were diagnosed based on medical history, clinical manifestations, seasonality of onset, and peripheral hypothermia. Later swelling and pain exacerbated, and after 1 month there were several tender, translucent hemorrhagic nodules in the previous right thumb toe chilblain and right foot. The skin biopsy was a metastatic gland consistent with primary breast cancer. Cancer, local radiotherapy for the above lesions.