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应用免疫组织化学方法对人体肺癌表皮生长因子受体的表达进行了研究。实验结果表明:表皮生长因子受体表达定位于细胞浆和细胞膜。表皮生长因子受体表达与人体肺癌的组织学类型及病理分级有关。小细胞肺癌阳性表达率明显低于其他各型肺癌(非小细胞癌)的阳性表达率。
Immunohistochemistry was used to study the expression of epidermal growth factor receptor in human lung cancer. The experimental results show that the expression of epidermal growth factor receptor is located in the cytoplasm and cell membrane. Epidermal growth factor receptor expression is associated with the histological type and pathological grade of human lung cancer. The positive rate of small cell lung cancer was significantly lower than that of other types of lung cancer (non-small cell carcinoma).