自1965年,祝氏首次用654—2治疗感染性休克以来,654—2在临床各科的应用日益广泛,今就其在儿科临床的应用阐述如下。(一)治疗再生障碍性贫血周氏等报道,用654—2 0.5～2毫克/公斤加入葡萄糖液中静点,治疗85例再障患者,结果基本治愈7例,缓解20例,明显改善46例,有效率达86%。其机理可能是使骨髓神经得到调节,并使骨髓血流加速,毛细血管增生,从而改善造血微环境,刺激造血干细胞生长。(二)治疗特发性血小板减少性紫癜方法是以654—2每次0.5～1毫克/公斤,每日1次静点,10日为1疗程。张氏用本法治疗24例,并与激素治疗组对照,结果24例中临床控制22例,显效1例,好转1例,升血小板作用明显优于对照组,用药 Since 1965, the first time I wish to use 654-2 for the treatment of septic shock, 654-2 has become more and more widely used in all clinical departments and its clinical application in pediatrics is as follows. (A) treatment of aplastic anemia Zhou’s report, with 654-2 0.5 ~ 2 mg / kg glucose solution was added to the static point, the treatment of 85 cases of aplastic anemia patients, the results were basically cured in 7 cases, 20 cases were alleviated, significantly improved 46 For example, the effective rate of 86%. The mechanism may be to make bone marrow nerve regulation, and to accelerate bone marrow blood flow, capillary proliferation, thereby improving hematopoietic microenvironment and stimulate hematopoietic stem cell growth. (B) of the treatment of idiopathic thrombocytopenic purpura method is 654-2 each 0.5 ~ 1 mg / kg, daily static point, on the 10th for a course of treatment. Zhang’s treatment of 24 cases with this method, and hormone therapy group control, the results of 24 cases of clinical control in 22 cases, 1 case markedly improved in 1 case, platelet effect was significantly better than the control group, medication