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博莱霉素的结构虽已提出并经修正,但因其分子甚为复杂及非结晶性故仍未能确认。本文报道了去甲博莱霉素 A_2与博莱霉素 A_2的全合成,并与相应天然品的性质作了比较。
Although the structure of bleomycin has been proposed and amended, it is still not confirmed because of its complex molecule and non-crystallinity. This paper reports the complete synthesis of bleomycin A_2 and bleomycin A_2, and compares them with the properties of corresponding natural products.