本文根据细胞动力学对力学因素的响应，设计研制了一种四点弯曲单向交变应变加载装置。通过对Wistar大鼠成骨细胞的试验，以及流式细胞仪（FCM）对细胞DNA分析检测的结果，表明研制是成功的，并可广泛使用于内皮细胞、成纤维细胞、平滑肌细胞、心肌细胞等组织工程和生物医学工程、人机工程学、细胞力学方面的研究。 Based on the response of cell dynamics to mechanical factors, a four-point bending unidirectional alternating strain loading device was designed and developed. The test of osteoblasts in Wistar rats and the results of cell DNA analysis by flow cytometry (FCM) showed that the development was successful and can be widely used in endothelial cells, fibroblasts, smooth muscle cells, and cardiomyocytes. Such as tissue engineering and biomedical engineering, ergonomics, cell mechanics research.