论文部分内容阅读
早在19世纪50年代即明确胃腺癌与胃化生(IM)有相关性,并建立了胃癌模型,证明从慢性胃炎到萎缩性胃炎的肠化生的病理过程,且有少数发展为结构不良和癌。近年来,美国胃癌的发病率有所下降,但是癌的部位有从远段向近段变化的趋势。为了验证胃贲门IM是否为贲门癌的癌前病变,研究者在3年中对有贲门IM者进行了随访。 病人和方法:随访组35例贲门IM的病人,诊断时未发现结构不良,贲门IM的诊断是在胃食管交界(EGJ)下2厘米内活检病理发现IM作出的。为了清楚地显示IM,内镜下用美蓝作活体染色,在染色阳性区取活检。切片应用
As early as the 1850s, it was clear that gastric adenocarcinoma was related to gastric metaplasia (IM) and a gastric cancer model was established to prove the pathological process of intestinal metaplasia from chronic gastritis to atrophic gastritis with a few developing into poor structure And cancer. In recent years, the incidence of gastric cancer in the United States has declined, but the location of the cancer tends to change from the distal segment to the proximal segment. In order to verify whether gastric cardia IM is a precancerous lesion of cardia cancer, the investigators followed up with cardia IM in 3 years. PATIENTS AND METHODS: A total of 35 patients with cardiac IM at follow-up were diagnosed without structural dysfunction. Diagnosis of cardia IM was performed within 2 cm of biopsy pathology IM at the gastro-oesophageal junction (EGJ). In order to clearly show IM, endometrial staining with methylene blue for in vivo staining, biopsy in the positive staining area. Slice application