量子点是一类直径小于100nm的半导体纳米晶粒,是一种很有潜力的荧光标记物。量子点标记探针广泛应用于肿瘤的体内外研究,尤其是肿瘤靶向成像、前哨淋巴结成像、肿瘤示踪、肿瘤细胞及亚细胞结构成像及肿瘤标志物检测等。基于量子点技术建立一种高灵敏度、高特异性的肿瘤检测体系,是量子点未来应用研究的一个重要方向。 Quantum dots are a class of semiconductor nanocrystals with diameters less than 100 nm and are promising fluorescent labels. Quantum dot-labeled probes are widely used in in vitro and in vivo tumor research, especially tumor targeted imaging, sentinel lymph node imaging, tumor tracing, imaging of tumor cells and subcellular structures, and detection of tumor markers. The establishment of a high-sensitivity and high-specificity tumor detection system based on quantum dot technology is an important direction for the future application of quantum dots.