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目的 :比较常规冠脉造影、冠脉造影计算机定量分析和冠脉内超声 ,探讨冠脉内超声在支架内再狭窄研究中的应用。方法 :对 4 1例病人的 4 5处病变置入支架治疗 ,术前、术后采用冠脉造影和冠脉内超声系列检查。结果 :术前、术后即刻以及术后 3个月、6个月冠脉造影病变狭窄程度分别是 87.4± 11.3% ,8± 9.2 % ,4 9.8±10 .7%和 5 7.2± 12 .3% ;QCA示狭窄程度分别为 6 1.4± 16 .0 % ,3.3± 13.3% ,2 4 .8± 2 0 .6 %和 2 8.9±18.8% ,两种方法得出的结果有显著性差异。冠脉内超声示术后即刻以及术后 3个月、6个月的支架横断面积从 8.2 5± 1.83mm2到 95 8± 2 .5 9mm2 (P <0 .0 0 1)和 10 .4 6± 2 .6 9mm2 (P <0 .0 1) ,支架横断面积进行性扩大 ,前后比较在统计学上有显著性差异。结论 :ICUS是研究支架内再狭窄的一个最直接、客观的方法 ,安全、易操作。
Objective: To compare the conventional coronary angiography, coronary angiography computerized quantitative analysis and intracoronary ultrasound to explore the application of intracoronary ultrasound in the study of in-stent restenosis. Methods: Forty-five patients with 41 lesions were treated with stents. Coronary angiography and intracoronary ultrasound were performed before and after surgery. Results: The stenosis degree of coronary angiography was 87.4 ± 11.3%, 8 ± 9.2%, 4 9.8 ± 10.7% and 5 7.2 ± 12.3, respectively, preoperatively, immediately after operation and at 3 months and 6 months after operation %; QCA showed stenosis of 6 1.4 ± 16.0%, 3.3 ± 13.3%, 24.8 ± 20.6% and 29.9 ± 18.8%, the results obtained by the two methods were significantly different. Coronary sonography showed that the cross-sectional area of the stent immediately after operation and at 3 months and 6 months after operation were from 8.2 5 ± 1.83 mm 2 to 95 8 ± 2.59 mm 2 (P <0.01 01) and 10 4.6 ± 2.9mm2 (P <0.01), and the cross-sectional area of the scaffold was enlarged in a statistically significant manner. Conclusion: ICUS is one of the most direct and objective methods to study in-stent restenosis, which is safe and easy to operate.