常染色体显性成人多囊肾疾病(AP-KD)是男性最常见的显性遗传性疾病之一,发病率为1/1000。虽然透析和移植的进展已使预后改善,但APKD对家庭和社会仍是一个相当大的负担。在整个需肾移植治疗的患者中,约占10%。尽管这种疾病很重要,但对其发病机理尚不了解。因此,唯一 Autosomal dominant adult polycystic kidney disease (AP-KD) is one of the most common dominant genetic diseases in men, with an incidence of 1 in 1000. Although advances in dialysis and transplantation have improved the prognosis, APKD is still a considerable burden on families and society. In the entire kidney transplant patients, about 10%. Although the disease is important, its pathogenesis is not known. So, only