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目的探讨平均红细胞体积(MCV)、红细胞分布宽度(RDW)在缺铁性贫血(IDA)与地中海贫血(地贫)的鉴别诊断中的意义。方法利用全自动血液细胞分析仪(MEACKMANCOULTERLH750)检测55例IDA、15例地贫和95例正常人的MCV和RDW。结果与正常组比,IDA和地贫组MCV降低,IDA组的RDW增高,差异均有统计学意义(P<0.01);地贫组RDW与正常组比(P>0.05),但与IDA组比(P<0.01)。结论MCV和RDW可作为IDA早期诊断的参考指标,RDW对IDA与地贫的鉴别诊断有重要价值。
Objective To investigate the significance of mean corpuscular volume (MCV) and erythrocyte distribution width (RDW) in the differential diagnosis of iron deficiency anemia (IDA) and thalassemia (thalassemia). Methods MCV and RDW in 55 cases of IDA, 15 thalassemia and 95 normal controls were detected by MEACKMAN COULTER LH750. Results Compared with the normal group, the MCV of IDA group and thalassemia group were decreased, while the RDW of IDA group was significantly higher than that of IDA group (P <0.01). The RDW of thalassemia group was significantly higher than that of normal group (P> 0.05) (P <0.01). Conclusion MCV and RDW can be used as reference indicators for early diagnosis of IDA. RDW is of great value in the differential diagnosis of IDA and thalassemia.