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对97例鼻咽癌、86例鼻咽部良性疾病和100例健康人进行血清脂质结合唾液酸(LSA)测定。结果显示:鼻咽癌组血清LSA含量明显高于鼻咽部良性疾病组及健康人组;不同病理类型的鼻咽癌血清LSA有所差异;随着鼻咽癌临床分期的发展,血清LSA含量逐渐增加,鼻咽癌复发或转移则血清LSA明显增高。结果表明:血清LSA测定有助于鼻咽癌的诊断、分型、分期及监测预后。
Serum lipid-bound sialic acid (LSA) was measured in 97 cases of nasopharyngeal carcinoma, 86 cases of nasopharyngeal benign disease and 100 cases of healthy people. The results showed that serum LSA levels in nasopharyngeal carcinoma group were significantly higher than those in benign nasopharyngeal group and healthy group. LSA of different pathological types of NPC were different. With the development of clinical stage of nasopharyngeal carcinoma, serum LSA level Gradually increased, recurrence or metastasis of nasopharyngeal carcinoma serum LSA was significantly higher. The results showed that serum LSA was helpful for the diagnosis, classification, staging and prognosis of NPC.