针对柴胡桂枝汤加芍药的抗癫痫作用,作者曾对该方的药理作用及作用机制进行了研究,并且对该方在抗痉挛作用中起主要作用的芍药进行了同样的研究,得到一些结果。此次为更明确地搞清芍药的抗痉挛作用,以钴病灶造成大鼠癫痫模型,给此种模型大鼠连续口服芍药提取物,研究其对神经细胞损伤及痉挛脑波出现的作用。 In view of the antiepileptic effect of Chaihu Guizhi Tanga, the author studied the pharmacological action and the mechanism of action of this drug, and conducted the same research on the pharmacological agent that played a major role in the anti-caries effect, and obtained some results. In order to clearly understand the anti-spasm effects of peony, a rat model of epilepsy was established with cobalt lesions. This model rat was given oral peony extracts continuously to study its effects on nerve cell damage and the occurrence of epilepsy waves.