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目的:甲诺参洗剂的制备及临床应用。方法:制定制备工艺,采取随机单盲对照,将444例细菌性及滴虫性阴道炎患者随机分为治疗组和对照组。治疗组204例用甲诺参洗剂。对照两组各120例分别应用利夫康乐溶液及百艾洗剂,连续用药14d。结果:治疗组临床治愈率分别为76.9%,90%,总有效率分别为96.2%及100%;对照组1治愈率分别为40%,30%,总有效率分别为71.7%,56.7%;对照组2治愈率分别为33.3%,43.3%,总有效率分别为61.7%,81.6%。治疗组疗效明显优于对照组,两组间差异有极显著性(P<0.01)。结论:该制剂处方设计合理,制备简单,临床疗效显著,且无不良反应,安全、价廉,值得推广。
Objective: Preparation and clinical application of forenones ginseng lotion. Methods: The preparation process was designed and randomized single-blind control was used. 444 patients with bacterial and trichomoniasis vaginitis were randomly divided into treatment group and control group. 204 patients in the treatment group were treated with gentrolone lotion. In the control group, 120 patients in each group were treated with Levicon solution and Baiai lotion, respectively, for 14 days. Results: The clinical cure rates of the treatment group were 76.9% and 90%, respectively, and the total effective rate was 96.2% and 100%. The cure rate of the control group 1 was 40% and 30% respectively. The total effective rate was 71.7% and 56.7% respectively. The cure rate of the control group 2 was 33.3% and 43.3% respectively, and the total effective rate was 61.7% and 81.6%, respectively. The efficacy of the treatment group was significantly better than that of the control group, and the difference between the two groups was extremely significant (P<0.01). Conclusion: The formulation has a reasonable prescription, simple preparation, significant clinical efficacy, no adverse reactions, and is safe and inexpensive. It is worthy of promotion.