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目的探讨新辅助化疗对中晚期乳腺癌的临床疗效。方法回顾性分析中晚期乳腺癌新辅助化疗38例患者的临床资料。结果辅助化疗患者总有效率(CR+PR)为66.83%,其中临床完全缓解(CR)15.67%,部分缓解(PR)51.16%,肿瘤无变化33.17%,无病变进展病例。所有患者均未发生严重不良反应。结论乳腺癌对术前化疗有较高的缓解率,且对改善乳腺癌预后有重要意义。
Objective To investigate the clinical effect of neoadjuvant chemotherapy on advanced breast cancer. Methods The clinical data of 38 patients with advanced breast cancer treated by neoadjuvant chemotherapy were retrospectively analyzed. Results The total effective rate (CR + PR) of patients with adjuvant chemotherapy was 66.83%, of which clinical complete response (CR) 15.67%, partial response (PR) 51.16%, no tumor change 33.17%, no progression of disease. No serious adverse reactions occurred in all patients. Conclusion Breast cancer has a high response rate to preoperative chemotherapy and is of great importance to improve the prognosis of breast cancer.