近代对消化性溃疡研究结果表明,“无酸即无溃疡”的理论依然是正确的。在这种理论的指导下,常用制酸剂来治疗消化性溃疡,近期效果是相当成功。Grossman在攻击因子方面提出的壁细胞受体理论,已知壁细胞表面有乙酰胆硷、组织胺和胃泌素三种独立受体,对各种受体给予单剂量酸分泌刺激,可引起相应的酸分泌。随着受体拮抗剂阿托品、胃必疗(Pirenzepine)以及甲氰咪胍和丙谷胺(Proglumide)等药物的产生,确认壁 Modern research on peptic ulcer results show that “no acid or ulcer” theory is still correct. Under the guidance of this theory, commonly used antacids to treat peptic ulcer, the recent effect is quite successful. Grossman proposed the theory of parietal cell receptors in terms of aggression factors. It is known that parietal cells have three independent receptors, acetylcholine, histamine and gastrin. Single-dose acid secretion stimulation on various receptors can cause corresponding Acid secretion. With the emergence of receptor antagonists atropine, Pirenzepine, and other drugs such as cimetidine and Proglumide,