Stevens—Johnson氏综合征亦称粘膜—皮肤—眼部综合征,其早期特点是高热,皮肤出现渗出性多型性红斑,并有伪膜性结膜炎,以及口腔、会阴粘膜溃疡,晚期常因破坏泪腺而遗留实质性眼干燥症,使病人长期蒙受极大痛苦,并造成严重视力障碍。对此病尚缺少有效治疗方法。半年来,我们采用电解封闭泪小点及泪小管的方法治疗54例,对其中38人进行了追踪观察。一般临床资料:本文共38例,女24人,男14人,女多于男;大部分病人为11～40岁;患病距就诊时间最短20天,最长7年;38人中 Stevens-Johnson’s syndrome, also known as mucocutaneous-ocular syndrome, is characterized by early onset of hyperthermia, exudative erythema on the skin and pseudomembranous conjunctivitis, as well as oral and perineal mucosal ulceration, Due to damaging the lacrimal gland and leaving the real eye xerophthalmia, the patient suffered great pain for a long time, and cause serious visual impairment. The disease is still lack of effective treatment. For six months, we used 54 cases of electrolytic closure of punctum and lacrimal duct, 38 of them were followed up. General clinical data: This article a total of 38 cases, 24 females, 14 males, more females than males; most of the patients for the 11 to 40 years old; sick from the shortest treatment time of 20 days, up to 7 years; 38