硝喹Nitroquine(Cl679,简称679),1970年Thompson氏报道该药对鼠疟、猴疟有较好的抑制作用,以后未再见有报道。上海医药工业研究院于1971年合成,第三军医大学进行了抗疟作用及毒理研究。实验研究表明:对鼠疟、鸡疟及猴疟的红细胞内期和组织期都有较好的抗疟作用,并对鸡疟、猴疟以及人疟的孢子增殖均有阻断作用。经过药理、毒理观察和健 Nitroquine (Cl679, referred to as 679), 1970 Thompson’s reported that the drug has a good inhibitory effect on murine malaria, malaria, did not see good news later. Shanghai Institute of Pharmaceutical Industry in 1971 synthesized, the Third Military Medical University conducted a malaria and toxicological studies. Experimental studies have shown that there is a good anti-malarial effect on the erythrocytic stage and tissue stage of murine malaria, malaria and monkey malaria, and blocking the proliferation of sporozoites of malaria, chlamydia malaria and malaria. After pharmacological, toxicological observation and health