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目的:观察中西医结合多法联用治疗反流性食管炎的临床疗效及预防其复发的效果。方法:将明确诊断为反流性食管炎患者108例随机分为两组:对照组52例,给予奥美拉唑肠溶胶囊及莫沙比利分散片口服治疗。中西医结合治疗组56例,在对照组治疗的基础上加用中药抗反流合剂口服及中药糊剂卧位服药疗法治疗,疗程均为20天。结果:中西医结合治疗组和对照组疗效无明显差异(P>0.05);但中西医结合治疗组在疗程结束后的1个月、3个月及6个月复发率分别为5.4%、7.1%、11.1%;明显低于对照组17.3%、25.0%、35.3%,差异有统计学意义(P<0.05)。结论:中西医结合治疗组可明显降低反流性食管炎的复发率(P<0.05),值得在临床进一步推广应用。
Objective: To observe the clinical curative effect and prevention of recurrence of reflux esophagitis treated by integrated traditional Chinese and western medicine. Methods: One hundred and eight patients diagnosed as reflux esophagitis were randomly divided into two groups: control group (n = 52) and oral omeprazole enteric-coated capsules and mosapride dispersible tablets. Integrative Medicine group 56 cases, in the control group based on the treatment with traditional Chinese medicine anti-reflux mixture of oral and traditional Chinese medicine treatment of lying supine medication, treatment were 20 days. Results: There was no significant difference between the treatment group and the control group (P> 0.05). However, the recurrence rates at the one, three and six months after the end of treatment were 5.4%, 7.1 %, 11.1% respectively, which was significantly lower than that of the control group (17.3%, 25.0%, 35.3%, P <0.05). Conclusion: Integrative Medicine group can significantly reduce the recurrence rate of reflux esophagitis (P <0.05), it is worth further promotion in clinical application.