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目的分析药品不良反应的发生特点与一般规律,促进合理用药。方法对某院2008年1月1日至2009年9月30日间收集到的208例ADR报告进行回顾性分析。结果208例不良反应中,涉及抗菌药物94例,占45.19%,中药注射剂56例,占26.92%。静脉给药引起的不良反应155例,占74.52%。ADR的临床表现以皮肤及其附件损伤最为常见,其次是消化系统损害等。结论应加强专业人员的业务培养和素质培养,合理使用抗感染药物及中药注射剂,减少不合理用药,以减少和避免ADR的发生。
Objective To analyze the characteristics and general rules of adverse drug reactions and to promote rational drug use. Methods A retrospective analysis of 208 ADRs collected in a hospital from January 1, 2008 to September 30, 2009 was performed. Results Among the 208 adverse reactions, 94 were antibiotics, accounting for 45.19%, and 56 were Chinese traditional medicine injection, accounting for 26.92%. 155 cases of adverse reactions caused by intravenous administration, accounting for 74.52%. The clinical manifestations of ADR damage to the skin and its accessories the most common, followed by digestive damage and so on. Conclusion It is necessary to strengthen professional training and quality training professionals, the rational use of anti-infective drugs and Chinese medicine injection, to reduce irrational use of drugs to reduce and avoid the occurrence of ADR.