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目的:分析缬沙坦与氢氯噻嗪复方制剂联合治疗轻中度原发性高血压的临床疗效,为后期相关治疗工作的开展提供参考。方法:选择收治治疗的80例原发性高血压患者,作为此次试验研究对象。按照临床用药方案的不同,分为实验组(缬沙坦、氢氯噻嗪复方制剂联合用药)和参照组(缬沙坦单一用药)。对比两组患者的临床疗效以及临床用药安全性。结果:对两组高血压患者的总有效率进行比较,实验组高于参照组,P<0.05。对两组患者治疗前后舒张压以及收缩压变化情况对比,实验组事实验前后差异具有统计学意义P<0.05。结论:缬沙坦联合氢氯噻嗪复方制剂治疗轻中度原发性高血压效果显著,且无明显药物毒副作用,值得推广。
Objective: To analyze the clinical efficacy of combination valsartan and hydrochlorothiazide in the treatment of mild to moderate essential hypertension, and to provide reference for the development of the related treatment. Methods: 80 cases of patients with primary hypertension were selected for treatment, as the object of this study. In accordance with the different clinical programs, divided into experimental group (valsartan, hydrochlorothiazide combination preparation) and the reference group (valsartan single-agent). The clinical efficacy and clinical medication safety of two groups were compared. Results: The total effective rate of patients with hypertension was compared, the experimental group was higher than the reference group, P <0.05. Comparing the changes of diastolic blood pressure and systolic blood pressure before and after treatment in both groups, there was significant difference before and after the experimental group events (P <0.05). Conclusion: The combination of valsartan and hydrochlorothiazide is effective in treating mild-to-moderate essential hypertension with no apparent side effects of drugs, which is worthy of promotion.