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曾证明如从胎膜破裂至分娩时间超过24小时,有增加母亲和胎儿发病率及更高的围产期死亡的危险。以前的研究已证实足月妊娠胎膜早破(PROM)病例,口服PGE_2和静注催产素有同样的效果。但静注催产素能显著缩短引产至分娩的时间。本研究的目的在于阐明对PROM病例引产,与口服PGE_2相比,给予去氨基催产素(demoxytocin)是否与静注催产素有同样的优点。 Odense大学医院产科两年接收193例PROM孕妇住院。孕龄都超过37周,以头先露分娩活婴。破膜后至少6小时无宫缩,宫口扩张小于3cm,宫
It has been demonstrated that there is a risk of increased maternal and fetal morbidity and higher perinatal death from rupture of the membranes to delivery of more than 24 hours. Previous studies have demonstrated full-term gestational premature rupture of membranes (PROM) cases, oral PGE 2 and intravenous oxytocin have the same effect. But intravenous oxytocin can significantly shorten the time from induction of labor to childbirth. The aim of this study was to elucidate whether induction of labor in PROM patients has the same benefit of intravenous oxytocin as demoxytocin versus oral PGE 2. Odense University Hospital obstetrics receiving 193 cases of PROM pregnant women hospitalized for two years. Gestational age are more than 37 weeks, first dew childbirth live baby. After rupture of membranes at least 6 hours without contractions, cervix expansion less than 3cm, Palace