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对宫颈癌,尽管高剂量率后装治疗的应用已有20年,但与低剂量率治疗相比仍缺少经验。本研究系前瞻性随机临床试验比较低剂量率与高剂量率腔内后装对宫颈癌的治疗效果。 本组患者系自1986年6月至1989年6月间的482例以前未曾治疗过的宫颈浸润癌患者。在治疗前先根据国际妇产科联盟(FIGO)分期法进行行临床分期,并进行各种检查,包括血像、血生化、胸片,静脉肾盂造影、膀胱镜检查及宫颈活检。根据临床分期、肿瘤的大小及局部解剖情况把病人分成两组。第一组是以腔内治疗为主;第二组则以外照
Cervical cancer, despite the use of high-dose rate after-treatment for 20 years, still lacks experience compared with low-dose therapy. This study was a prospective randomized clinical trial comparing the efficacy of low dose rate and high dose rate intracavitary afterloading on cervical cancer. The patients were from 482 patients with previously untreated cervical invasive carcinoma between June 1986 and June 1989. Before treatment, according to the International Federation of Gynecology and Obstetrics (FIGO) staging clinical staging, and a variety of tests, including blood, blood biochemistry, chest X-ray, intravenous pyelography, cystoscopy and cervical biopsy. Patients were divided into two groups based on clinical stage, tumor size and local anatomy. The first group is based on endovascular treatment; the second group is based on the outside