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通过对３６例ＣＲＦ，非透析患者甲状腺激素的水平及８例血透患者血透前后甲状腺激素的变化进行观察，并以３０例正常成年人甲状腺激素作对比分析。发现ＣＲＦ患者Ｔ－３、Ｔ－４、ｒＴ－３、ＦＴ－３、ＦＴ－４、ＦＴ－４／ＦＴ－３均明显低于正常组（Ｐ＜０．０１）；ＣＲＦ非透析患者Ｔ－３、ｒＴ－３、ＦＴ－３、ＦＴ－４、ＦＴ－４／ＦＴ－３和Ｓｃｒ呈负相关；血透患者血透前后甲状腺激素无明显变化。结合文献探讨了ＣＲＦ患者继发性甲状腺机能低下症的机理。
The levels of thyroid hormones in 36 cases of CRF and non-dialysis patients and the changes of thyroid hormones before and after hemodialysis in 8 cases of hemodialysis patients were observed. Thirty cases of normal thyroid hormone were compared. The levels of T-3, T-4, rT-3, FT-3, FT-4 and FT-4 / FT-3 in patients with CRF were significantly lower than those in the normal group (P <0.01) 3, FT-3, FT-4, FT-4 / FT-3 and Scr. There was no significant change of thyroid hormones in hemodialysis patients before and after hemodialysis. The mechanism of secondary hypothyroidism in CRF patients was discussed in combination with the literature.