论文部分内容阅读
目的:对纳洛酮联合高压氧治疗新生儿缺血缺氧性脑病的临床效果进行分析探讨。方法:将2010年3月~2013年3月本院收治符合新生儿缺血缺氧性脑病诊断标准的102例患儿随机平均分为2组(各51例),对照组采取常规治疗,观察组在对照组基础上采用纳洛酮联合高压氧治疗方案。观察2组临床疗效及症状改善时间。结果:经治疗后对照组临床有效率为70.6%,观察组为92.2%,差异有统计学意义(P<0.05);观察组症状改善时间为6.89±3.0天短于对照组的9.88±2.43天,差异具有统计学意义(P<0.05)。结论:纳洛酮联合高压氧治疗新生儿缺血缺氧脑病疗效显著,值得在临床推广使用。
Objective: To analyze the clinical effect of naloxone combined with hyperbaric oxygen on neonatal hypoxic-ischemic encephalopathy. Methods: From March 2010 to March 2013, 102 children eligible for the diagnosis of neonatal hypoxic-ischemic encephalopathy in our hospital were randomly divided into two groups (n = 51). The control group was given routine treatment and observed Group based on the control group with naloxone combined with hyperbaric oxygen treatment. The clinical efficacy and symptom improvement in 2 groups were observed. Results: After treatment, the clinical effective rate was 70.6% in control group and 92.2% in observation group, the difference was statistically significant (P <0.05); the symptom improvement time in observation group was 6.89 ± 3.0 days shorter than 9.88 ± 2.43 days in control group , The difference was statistically significant (P <0.05). Conclusion: Naloxone combined with hyperbaric oxygen treatment of neonatal hypoxic-ischemic encephalopathy significant effect, it is worth in the clinical promotion.