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目的观察白玉参景脉通汤联合常规西药对痰瘀互阻型冠心病患者血清脂联素水平的影响。方法将60例痰瘀互阻型冠心病患者随机分为治疗组和对照组,每组30例。对照组予常规西药治疗,治疗组予常规西药结合中药白玉参景脉通汤。两组疗程均为2个月,观察临床疗效以及中医证候积分、血脂指标、脂联素水平的变化情况。结果 1治疗组、对照组总有效率分别为90.0%、70.0%;组间临床疗效比较,差异有统计学意义(P<0.05)。2治疗前后组内比较,治疗组心悸、气短、胸脘痞满、身体困重积分及总积分差异有统计学意义(P<0.05),对照组胸痛、气短、胸脘痞满积分及总积分差异有统计学意义(P<0.05);组间治疗后比较,胸脘痞满、身体困重积分及总积分差异有统计学意义(P<0.05)。3治疗前后组内比较,两组血脂各指标差异均无统计学意义(P>0.05),脂联素差异有统计学意义(P<0.05);组间治疗后比较,脂联素差异有统计学意义(P<0.05)。结论白玉参景脉通汤联合常规西药可有效缓解痰瘀互阻型冠心病患者的临床症状,并具有一定的上调血清脂联素水平的作用。
Objective To observe the effect of Baiyueshen Jingmaitong Decoction combined with conventional western medicine on serum adiponectin level in patients with phlegm and blood stasis syndrome. Methods Sixty patients with phlegm and blood stasis type of coronary heart disease were randomly divided into treatment group and control group, with 30 cases in each group. The control group was treated with conventional western medicine, while the treatment group was given conventional western medicine combined with traditional Chinese medicine Baiyu Shen Jingmai Tongtang. The two courses of treatment were 2 months, observe the clinical efficacy and TCM syndrome score, blood lipids, adiponectin level changes. Results 1 The total effective rates of the treatment group and the control group were 90.0% and 70.0%, respectively. The clinical efficacy of the two groups was statistically significant (P <0.05). 2 before and after treatment group comparison, the treatment group, heart palpitations, shortness of breath, chest fullness, full body weight integral and total score difference was statistically significant (P <0.05), control group chest pain, shortness of breath, chest fullness score and total score The difference was statistically significant (P <0.05). After treatment, there were significant differences in chest fullness, full body weight and total body weight (P <0.05). There was no significant difference between the two groups (P> 0.05). The difference of adiponectin was statistically significant (P <0.05). There was statistical difference in adiponectin between the two groups after treatment Significance (P <0.05). Conclusion Baiyu Shen Jing Maitong Decoction combined with conventional western medicine can effectively relieve the clinical symptoms of patients with phlegm and blood stasis syndrome, and has the effect of raising serum adiponectin level.