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目的探讨影响子宫平滑肌肉瘤预后的各种临床病理因素。方法应用SAS软件,作COX模型的危险度分析,共回顾分析了111例子宫平滑肌肉瘤的临床、病理资料及随访结果。结果患者年龄越大、临床-手术分期越晚,预后越差;病理诊断为子宫平滑肌肉瘤的比低度恶性平滑肌肉瘤和平滑肌肉瘤瘤变的预后明显为差。结论子宫平滑肌肉瘤的预后与患者年龄、临床-手术分期及病理诊断是否为平滑肌肉瘤有关。对于年轻患者,临床-手术分期为Ⅰ期,肿瘤局限,无弥漫性浸润者,具有保留附件的可能性。
Objective To explore various clinicopathological factors that affect the prognosis of leiomyosarcoma of the uterus. Methods SAS software was used to analyze the risk of COX model. A total of 111 cases of uterine leiomyosarcoma were retrospectively analyzed for clinical and pathological data and follow-up results. Results The older the patient and the later the clinical-surgical staging, the worse the prognosis; pathological diagnosis of uterine leiomyosarcoma is significantly worse than the prognosis of low grade leiomyosarcoma and leiomyosarcoma. Conclusion The prognosis of uterine leiomyosarcoma is related to the age, clinical-surgical stage and pathological diagnosis of leiomyosarcoma. For young patients, the clinical-surgical stage is stage I, the tumor is localized, and there is no diffuse infiltrates, with the possibility of retaining attachments.