Objective:To investigate the prevalence and spectrum of complementary and alternative medicine (CAM) application and its related-factors in Parkinson\'s disease (PD) patients in China.Methods:A structured questionnaire regarding the use of CAMs was administered to PD patients by face-to-face interview.Demographic and social variables,clinical characteristics and treatments,and the related factors of PD were also surveyed.Results:Ninety out of 113 patients (79.6％) reported that they had received CAMs treatment,of which 48.6％ (55/113) patients had received CAMs treatment for PD.The top 3 kinds of CAMs for PD were Chinese materia medica,rehabilitation exercise,and acupuncture ordinally.The source of information regarding CAMs treatment mainly came from relatives and friends (51.8％,73 cases),followed by physicians (31.9％,45 cases),and medias such as television,newspapers or the intemet (16.3％,28 cases).Fifty percent of CAM users reported a good therapeutic efficacy,whereas 39％ patients reported that they felt neither better nor worse after the treatment,while 11％ patients claimed worsening of symptoms.Multiple correspondence analyses survey found the main factors affecting the selectivity of CAMs ranked in the following order:income,education,occupation,habitation,age at onset,Hoehn and Yahr staging,PD duration,and gender.Conclusion:CAMs,especially Chinese materia medica,rehabilitation exercise,and acupuncture,are widely used for PD patients in China.