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IgA肾病 (IgAN)是我国常见的原发性肾小球疾病 ,近年研究发现 ,众多细胞因子对IgAN的发生、发展关系密切 ,白细胞介素 - 6 (IL - 6 )是众多细胞因子网络中的重要因子之一 ,肾脏许多固有细胞如系膜细胞、内皮细胞、上皮细胞均能分泌IL - 6 ,IL - 6又能刺激系膜
IgA nephropathy (IgA) is a common primary glomerular disease in China. Recent studies have found that many cytokines are closely related to the occurrence and development of IgAN. Interleukin - 6 (IL - 6) is involved in many cytokines One of the most important factors is that many innate cells in the kidney can secrete IL - 6, such as mesangial cells, endothelial cells and epithelial cells, while IL - 6 can stimulate mesangial cells