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Lambert-Eaton肌无力综合征(Lambert-Eaton Myasthenic Syndrom,LEMS)是累及神经肌肉接头处突触前膜乙酰胆碱释放部位的自体免疫性疾病。又称重症肌无力综合症、类重症肌无力。临床上分为癌性LEMS(50%~87%)和非癌性LEMS(13%~50%)两类。在癌性LEMS中以小细胞肺癌最为多见(占68%~
Lambert-Eaton Myasthenic Syndrom (LEMS) is an autoimmune disease involving the presynaptic acetylcholine release site at the neuromuscular junction. Also known as myasthenia gravis syndrome, myasthenia gravis. Clinically divided into cancerous LEMS (50% ~ 87%) and non-cancerous LEMS (13% ~ 50%) two categories. Small cell lung cancer is most common in cancerous LEMS (68% ~