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目的：观察尼可地尔联合地尔硫艹卓治疗心肌桥的临床疗效。方法将经冠脉造影明确诊断心肌桥的98例患者随机分为治疗组和对照组49例，对照组应用β受体阻滞剂进行治疗，治疗组应用尼可地尔联合地尔硫艹卓进行治疗，并对治疗效果进行了比较分析。结果治疗后2组患者ST段压低次数、持续时间均明显下降（P＜0．01），心肌缺血总负荷明显改善（P＜0．01），体力负荷持续时间、心肌缺血功率显著增加（P＜0．01），总缺血负荷显著降低（P＜0．01），且上述各指标治疗组均优于对照组（P＜0．01）。结论尼可地尔联合地尔硫艹卓治疗心肌桥效果明显，值得临床推广应用。“,”Objective To observe the cinical effect of nicorandil combined with diltiazem in the treatment of myocar -dial bridge .Methods 98 hospitalizad patients with myocardial bridge diagnosed coronary angiography were chosen as the re -search object.They were randomly divided into two groups:control group and treatment group ,each of 49 cases.The control group received β-blockers,while the treatment group received nicorandil combined with diltiazem .The treatment effect between the two groups was compared .Results After treatment,two groups of patients with ST segment depression in frequency and duration were significantly decreased (P<0.01);total ischemia burden significantly improved (P<0.01);physical load sus-tained time,myocardial ischemia power increased significantly (P<0.01);total ischemia burden decreased significantly (P<0.01);and the indexes of the treatment group were better than those of the control group (P<0.01).Conclusion Nicorandil combined diltiazem has a good clinical efficacy in the treatment of myocardial bridge .It is worthy of clinical application .